October 2, 2025Open Access

Evaluation of Immunomodulatory Activity and Subacute Toxicity of a Novel Non-Cyanide Dried Cassava Mash (DCM)

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Discussion

Evaluates immunomodulatory effects and subacute toxicity in mice and rats, suggesting DCM is safe for consumption.

DCM showed mild immunostimulatory activity, improving spleen cellularity in mice without adverse effects.
The study found significant increases in antibody-producing cell counts after DCM administration over 8 days.
A 28-day toxicity evaluation in rats revealed no significant changes in body weight or organ function, indicating safety.
Oral administration of DCM confirmed its potential as a functional food ingredient with health benefits.

Salako et al. (2025) studied this question.

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