Systemic Immune-Inflammation Index and Other Inflammation Biomarkers in the Diagnosis of Gestational Diabetes Mellitus

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Discussion

Retrospective cohort study shows differences in inflammation biomarkers in patients with GDM, indicating diagnostic potential.

Patients with gestational diabetes show significantly higher systemic immune-inflammation index values compared to controls, indicating inflammation's role in GDM.
The mean systemic immune-inflammation index for patients with GDM was 1280 ± 496, versus 1144 ± 400 for controls, with a p-value of 0.002 showing statistical significance.
This retrospective cohort study included 567 patients and compared various inflammation biomarkers between groups with and without GDM.
These findings highlight the potential of systemic immune-inflammation index and neutrophil-to-lymphocyte ratio as important markers in gestational diabetes diagnosis.

Bildacı et al. (2025) studied this question.

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