Histopathological Changes of Dexamethasone on Affected Lung of Rats

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Experimental study investigates lung tissue changes after glucocorticoid treatment in rats, suggesting toxicity.

Marked vascular changes occurred in the lungs after long-term dexamethasone treatment, indicating toxicity.
Post-mortem examination revealed significant inflammatory responses and necrosis in lung tissue samples.
Oral administration of 0.1 mg/kg dexamethasone for 10 weeks resulted in congestion and degeneration of bronchioles.
Histopathological findings suggest that dexamethasone may lead to adverse lung responses in treated rats.

Jawad et al. (2025) studied this question.

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View Full Paper

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Authors

Experimental study investigates lung tissue changes after glucocorticoid treatment in rats, suggesting toxicity.

Marked vascular changes occurred in the lungs after long-term dexamethasone treatment, indicating toxicity.
Post-mortem examination revealed significant inflammatory responses and necrosis in lung tissue samples.
Oral administration of 0.1 mg/kg dexamethasone for 10 weeks resulted in congestion and degeneration of bronchioles.
Histopathological findings suggest that dexamethasone may lead to adverse lung responses in treated rats.

Jawad et al. (2025) studied this question.

View Full Paper

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