October 1, 2025JAMA Network OpenOpen Access

Adverse Events Following Short-Course Systemic Corticosteroids Among Children and Adolescents

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Authors

JLJoão Pedro Lima SCSaifur Rahman Chowdhury WTWimonchat Tangamornsuksan

Discussion

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Implication

Systematic review reveals associations between systemic corticosteroids and adverse events in children, suggesting need for individualized approaches.

Key Points

Corticosteroids were associated with increased hyperglycemia and sleep problems in children.
Analysis found low certainty evidence of increased gastrointestinal bleeding risk from corticosteroid use.
Meta-analysis included 45 trials assessing adverse events in 6470 children aged 1 to 18 years.
Findings suggest that individualized corticosteroid use may be necessary based on associated risks.

Cite This Study

Lima et al. (2025) studied this question.

synapsesocial.com/papers/68dd91dafe798ba2fc499280 https://doi.org/10.1001/jamanetworkopen.2025.34953

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Implication

Systematic review reveals associations between systemic corticosteroids and adverse events in children, suggesting need for individualized approaches.

Adverse Events Following Short-Course Systemic Corticosteroids Among Children and Adolescents

Discussion

Member takes

Implication

Key Points

Cite This Study

Adverse Events Following Short-Course Systemic Corticosteroids Among Children and Adolescents

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

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