This review demonstrates the potential benefits of melatonin and vitamins in cancer treatment, suggesting promising avenues for integrative oncology.
Key Points
Combining melatonin with vitamins may improve tumor suppression and reduce treatment toxicity, enhancing patient outcomes.
Emerging evidence highlights melatonin's role in regulating oxidative stress and apoptosis, along with vitamins D, C, and E's protective benefits.
Despite promising preclinical findings, clinical studies on the synergy of melatonin and vitamins remain limited, indicating a need for further investigation.
Future research should explore optimal dosing, mechanistic insights, and conduct clinical trials to establish the efficacy of these combinations.