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October 1, 2025PLoS ONEOpen Access

Comparison of time to death and its predictors among hospitalized children with and without severe acute malnutrition at Mulanje District Hospital, Southern Malawi

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Authors

MPMasuzgo PajogoMNMiriam Ndholvu

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Overview

Retrospective cohort study reveals higher child mortality in non-SAM compared to SAM, indicating urgent care needs.

Key Points

  • Mortality rate among under-five children was notably higher in non-SAM at 21.2% compared to SAM at 8.4%.
  • The median time to death was significantly shorter for non-SAM children, averaging 1 day versus 5 days for SAM children.
  • Cox proportional hazards regression analysis identified critical factors affecting mortality rates, emphasizing the role of amoxicillin and referral.
  • The findings highlight the need for improved triage and intervention protocols for non-SAM children to reduce mortality.

Cite This Study

Pajogo et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cffe798ba2fc498d9ahttps://doi.org/10.1371/journal.pone.0333585
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment outcomes and associated factors of severe acute malnutrition among under-5 children in Jigjiga public hospitals, Somali region, Ethiopia: a retrospective cohort study2025
  2. 2Determinants of Hospital Length of Stay in Children Under 59 Months with Acute Severe Malnutrition: Insights from Eastern Democratic Republic of Congo2025
  3. 3Factors Influencing Recovery and Mortality in Children with Severe Acute Malnutrition (SAM): Insights from a Therapeutic Feeding Program2025
  4. 4Determinants of mortality in children aged 1-59 months hospitalised with malaria in Burkina Faso’ Sahel region: evidence from the Dori regional hospital centre2025
  5. 5Risk Factors Associated with Severe Acute Malnutrition Among Children Under Five Years of Age: A Systematic Review of Recent Studies2025