Prevalence of Hepatitis B and Hepatitis C Co-Infection and Alanine Transferase Levels in HIV-Positive Children at Faith Alive Foundation and PMTCT Centre Jos

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Cross-sectional study shows low hepatitis B co-infection and ALT elevation in HIV-positive children, indicating monitoring needs.

The prevalence of hepatitis B co-infection among HIV-positive children was only 0.8%, while hepatitis C was not detected.
Median alanine aminotransferase (ALT) levels were 19.0 IU/L, with 7.5% of participants exhibiting elevated values.
Significant associations were found between viral loads above 1000 copies/ml and elevated ALT levels in the surveyed children.
The study highlights the importance of ongoing monitoring of liver enzymes in HIV-infected children, despite low co-infection rates.

Ihekaike et al. (2025) studied this question.

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View Full Paper

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Authors

Cross-sectional study shows low hepatitis B co-infection and ALT elevation in HIV-positive children, indicating monitoring needs.

The prevalence of hepatitis B co-infection among HIV-positive children was only 0.8%, while hepatitis C was not detected.
Median alanine aminotransferase (ALT) levels were 19.0 IU/L, with 7.5% of participants exhibiting elevated values.
Significant associations were found between viral loads above 1000 copies/ml and elevated ALT levels in the surveyed children.
The study highlights the importance of ongoing monitoring of liver enzymes in HIV-infected children, despite low co-infection rates.

Ihekaike et al. (2025) studied this question.

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