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October 1, 2025Journal of the American Academy of Orthopaedic Surgeons

Relationship Between Conflict of Interest and Reported Outcomes After Upper Extremity Nerve Reconstruction Using Acellular Nerve Allografts: A Systematic Review

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Authors

DBDaniel BahatSFSean FrisbieSMSamantha Maasarani

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Overview

Systematic review reveals COI influences motor and sensory recovery in peripheral nerve repair outcomes.

Key Points

  • Motor recovery was significantly higher in COI studies at 69.8% compared to 14.1% in non-COI studies.
  • Sensory recovery also differed notably, with COI studies showing 25.9% versus 80.4% in non-COI studies.
  • The findings imply funding sources can affect outcome reporting and interpretation in nerve reconstruction.
  • Future research should focus on standardized assessments and independent studies to ensure unbiased clinical guidance.

Cite This Study

Bahat et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cbfe798ba2fc498a05https://doi.org/10.5435/jaaos-d-25-00622
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sensory Recovery Following Digital Nerve Repair Using Conduits Versus Autologous Nerve Grafts: A Systematic Review and Meta‐Analysis2026 · 1 citations
  2. 2Motor Function in the Setting of Nerve Allografts: Is This the Future of Facial Nerve Reconstruction?2025
  3. 3Application strategies of autologous and decellularized nerve grafts: Structural and functional recovery2025
  4. 4Combined long nerve allograft and nerve transfer for functional recovery of ulnar nerve: case study with longitudinal clinical and neurodiagnostic follow-up2025 · 1 citations
  5. 5Comparative Outcomes of Direct Versus Connector-Assisted Peripheral Nerve Repair2025