Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 2025Tropical Journal of Natural Product ResearchOpen Access

Molecular Docking Study of Standardized Lime (Citrus aurantiifolia) Peel Decoction as an Antidiabetic Herbal

View Full Paper
Ask AI
Bookmark
Share

Authors

YDYesi DesmiatyFXFrancis XavierHAHanifah Agusti

Discussion

Loading...

Member takes

Overview

Molecular docking reveals flavonoid compounds inhibit α-glucosidase and SGLT-2 in diabetes models, indicating potential uses.

Key Points

  • Molecular docking shows rutin inhibits α-glucosidase, α-amylase, and DPP-4, reinforcing its antidiabetic potential.
  • Compounds including hesperidin and naringin exhibited inhibitory effects on key diabetes-related enzymes like SGLT-2.
  • Ultrasonic-assisted extraction was utilized to obtain compounds from Citrus aurantiifolia peels for analysis.
  • ADMET predictions indicate active compounds in citrus have limited absorption but show no toxicity.

Cite This Study

Desmiaty et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cbfe798ba2fc4988f0https://doi.org/10.26538/tjnpr/v9i9.65
View Full Paper
Ask AI
Bookmark
Share