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October 1, 2025Pharmacognosy MagazineOpen Access

Review of the Mechanism of Triptolide in the Treatment of Lung Cancer

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Authors

DQDakai QinQZQinyuan ZhangDLDemin Lin

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Overview

This review analyzes triptolide’s mechanisms in lung cancer, highlighting its effects on apoptosis and tumor microenvironment.

Key Points

  • Triptolide shows significant anti-tumor effects through various mechanisms, enhancing treatment effectiveness.
  • The research indicates that triptolide induces apoptosis and suppresses metastasis in lung cancer cells.
  • Analysis reveals that triptolide also combats oxidative stress and regulates immune response in the tumor microenvironment.
  • A focus on cuproptosis suggests novel pathways for improving therapeutic strategies in lung cancer.

Cite This Study

Qin et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc498190https://doi.org/10.1177/09731296251372724
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  1. 1Triptolide-induced Pyroptosis: A Promising Strategy for Cancer Therapy2025
  2. 2Immune mechanisms and therapeutic advances in lung cancer: A comprehensive review2025
  3. 3Lung Cancer Management: A Comprehensive Review with Special Focus on Natural Remedies and Bioactive Compounds2025
  4. 4Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression2025
  5. 5Research Progress on the Mechanism Exploration and Clinical Application of Traditional Chinese Medicine in Treating Non-Small Cell Lung Cancer2025