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October 1, 2025European Journal of Clinical Investigation

The intergenerational effects of low parental socio‐economic position on cardiometabolic and inflammatory outcomes: A systematic review and meta‐analysis

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Authors

JRJuan Carlos RivillasÉCÉmilie CourtinEWEleanor Winpenny

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Overview

Systematic review highlights associations between low parental socio-economic position and cardiometabolic, inflammatory markers in adults.

Key Points

  • Lower parental socio-economic position is linked to higher blood pressure in adult offspring, indicating increased health risks.
  • Pooled analysis from 12 studies demonstrated significant elevations in C-reactive protein levels associated with low parental SEP.
  • Research shows gender-specific variations in the impact of parental socio-economic position on adult inflammatory markers.
  • The review suggests exploring mechanistic pathways and life-course timing to understand the health impacts of parental socio-economic position.

Cite This Study

Rivillas et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc497f7chttps://doi.org/10.1111/eci.70125
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