Can the Systemic Immune-inflammation Index be Used as a Predictive Marker for Short- and Mid-term Mortality in Aortic Dissection?

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Analysis reveals systemic immune-inflammation index predicts mortality in aortic dissection patients, suggesting its clinical utility.

The systemic immune-inflammation index significantly predicts in-hospital mortality in acute type A aortic dissection patients, with a mortality rate of 24.7%.
Group B patients, with SII ≥1334.9, had higher mortality at P = 0.016, indicating the importance of SII in assessing patient risk.
Cox regression analysis identified several factors as independent predictors of mortality, including SII and cardiopulmonary bypass duration.
While SII is a promising biomarker for short-term outcomes, further studies are needed to evaluate its mid-term significance.

Kaplan et al. (2025) studied this question.

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Authors

Analysis reveals systemic immune-inflammation index predicts mortality in aortic dissection patients, suggesting its clinical utility.

The systemic immune-inflammation index significantly predicts in-hospital mortality in acute type A aortic dissection patients, with a mortality rate of 24.7%.
Group B patients, with SII ≥1334.9, had higher mortality at P = 0.016, indicating the importance of SII in assessing patient risk.
Cox regression analysis identified several factors as independent predictors of mortality, including SII and cardiopulmonary bypass duration.
While SII is a promising biomarker for short-term outcomes, further studies are needed to evaluate its mid-term significance.

Kaplan et al. (2025) studied this question.

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