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October 1, 2025Pakistan Journal of Medicine and DentistryOpen Access

Insights into Dengue Vaccine Development: Highlighting Serotype Diversity, Safety Concerns, and the Promise of AI

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Authors

SNSitara NasarHKHafiz Muhammad Haseeb Khaliq

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Overview

Observational analysis highlights vaccine effectiveness and safety concerns in dengue populations, suggesting AI can enhance development strategies.

Key Points

  • Vaccine performance varies due to dengue serotype diversity and risks linked to antibody-dependent enhancement.
  • TAK-003 shows efficacy of 85.9% against hospitalization, underscoring the importance of careful deployment in seronegative individuals.
  • Current research incorporates AI-based strategies for real-time genomic surveillance and predictive modeling to improve vaccine safety.
  • Engaging new technologies and rigorous science can drive a path toward an effective and equitable dengue vaccine.

Cite This Study

Nasar et al. (2025) studied this question.

synapsesocial.com/papers/68dd89defe798ba2fc497d26https://doi.org/10.36283/ziun-pjmd14-4/001
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