Metabolomics of abdominal adipose tissue samples collected from patients with obesity – a critical review

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This review evaluates metabolomic studies on adipose tissue, identifying differences in lipid metabolism and inflammatory pathways.

Metabolomics offers new insights into adipose tissue's role in obesity and metabolic dysfunction, with a focus on depot-specific differences.
Existing studies show VAT exhibits a pro-inflammatory and lipolytic profile, while SAT is involved in lipid storage and insulin regulation.
Methodological discrepancies in metabolomics contribute to inconsistency in understanding adipose tissue's metabolic functions and health impacts.
Future research must standardize methodologies and improve population diversity to enhance understanding of adipose tissue's variability in obesity.

Alina Jaroch (2025) studied this question.

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