September 25, 2025

Effectiveness of Cognitive Behavioral Therapy, Physical Therapy, and TNF Inhibitors in Managing Chronic Lower Back Pain in Ankylosing Spondylitis Patients: A Randomized Controlled Trial

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Discussion

Randomized controlled trial shows improved outcomes with TNF inhibitors, physical therapy, and CBT in patients, highlighting their effectiveness.

The combined therapy group exhibited significant improvements in pain intensity and functional status.
Pain scores dropped an average of 4.3 points in the multidisciplinary group compared to lower reductions in mono-therapy.
Statistical analysis confirmed the superiority of the combined intervention over single treatments with high significance.
Findings suggest a need for larger, multicenter trials to explore long-term effects and wider application of integrated treatment models.

Wajahat et al. (2023) studied this question.

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Randomized controlled trial shows improved outcomes with TNF inhibitors, physical therapy, and CBT in patients, highlighting their effectiveness.