September 25, 2025Orthopaedic SurgeryOpen Access

Pediatric Scoliosis in Osteogenesis Imperfecta: From Genetic Mechanisms to Therapeutic Strategies

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Scoliosis significantly impacts the quality of life in pediatric patients with osteogenesis imperfecta, leading to severe complications.
Early onset and rapid progression characterize scoliosis in osteogenesis imperfecta, making treatment particularly challenging.
Contemporary molecular-genetic research offers insights into spinal deformities, helping to identify risk factors associated with their progression.
Surgical and conservative approaches for treating scoliosis in osteogenesis imperfecta are reviewed, with a focus on new therapeutic strategies.

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This review discusses scoliosis progression in osteogenesis imperfecta, highlighting genetic factors and potential therapeutic strategies.

Muldiiarov et al. (2025) studied this question.

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This review discusses scoliosis progression in osteogenesis imperfecta, highlighting genetic factors and potential therapeutic strategies.