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September 25, 2025Journal of Applied PhysiologyOpen Access

Systemic and regional hemodynamic and (de)oxygenation responses across repeated breath-holds

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Authors

AEAntonis EliaMGMikael GennserOEOla Eiken

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Overview

Observational analysis mapped regional hemodynamic and deoxygenation responses in subjects, indicating varied dynamics during breath-holds.

Key Points

  • Deoxygenation responses change significantly across repeated breath-holds, highlighting important timing variations.
  • During initial breath-holds, cerebral cO2 Hb dropped substantially, yet subsequent attempts showed diminished responses.
  • A triphasic response in peripheral tissue (de)oxygenation was observed, with notable differences in the first attempt.
  • The study assessed 15 volunteers, revealing crucial insights about cardiovascular stability and gas exchange across trials.

Cite This Study

Elia et al. (2025) studied this question.

synapsesocial.com/papers/68d5e205bd7882ccb9b86885https://doi.org/10.1152/japplphysiol.00508.2025
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