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September 25, 2025Physiology

Zinc Transporters in diseases, including diabetes and related conditions

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Authors

WXWenjun XuXWXuan WangYGYukun Gao

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Overview

This review explores how zinc transporters influence diabetes and related disorders, indicating potential therapeutic strategies.

Key Points

  • Dysregulated zinc transporters may contribute to the onset and progression of diabetes and obesity.
  • Recent advances highlight the role of ZIP and ZnT families in cellular zinc homeostasis.
  • Controversies exist regarding the mechanistic involvement of specific transporters like ZnT8 in diabetes pathogenesis.
  • The review discusses the potential for targeting zinc transporters in precision medicine approaches.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68d5e205bd7882ccb9b86875https://doi.org/10.1152/physiol.00026.2025
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