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September 25, 2025Frontiers in MicrobiologyOpen Access

Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquía River, Argentina

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Authors

SRSusana Eugenia RuizUniversidad Católica de CórdobaFMFabrizzio Nicolas MorandiniConsejo Nacional de Investigaciones Científicas y TécnicasMPMaría Emilia PanzettaDuke University

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Implication

Study uncovers high levels of antibiotic-resistant bacteria in urban wastewater, highlighting AMR spread in rivers.

Key Points

  • Urban wastewater overflows serve as hotspots for the spread of antibiotic-resistant bacteria, particularly in river ecosystems.
  • Analysis of 62 water samples revealed that about 70% contained ESBL- and/or carbapenemase-producing bacteria, predominantly E. coli.
  • Whole-genome sequencing indicated complex resistomes and virulence factors linked to clinical resistance genes in aquatic bacteria.
  • These findings emphasize the urgent need for environmental AMR monitoring to tackle public health threats from antibiotic resistance.

Cite This Study

Ruiz et al. (2025) studied this question.

synapsesocial.com/papers/68d5e1ffbd7882ccb9b865a2https://doi.org/10.3389/fmicb.2025.1669531
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