September 25, 2025Open Access

Insights of hepatitis A virus disease burden in Indian subcontinent: why urbanized localities are vulnerable to disease outbreaks?

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Discussion

This analysis reveals rising HAV infections in adults and highlights the role of urbanization in disease spread.

Increased incidence of hepatitis A virus infections in adults indicates a shift from childhood immunity.
Hepatitis A virus primarily spreads through the fecal-oral route, affecting liver function and causing jaundice.
Molecular epidemiological studies confirm predominant genotypes IIIA and IA circulating in urban localities.
Vaccination efforts should focus on seronegative individuals to counteract the rising disease burden in urban settings.

Hussain et al. (2025) studied this question.

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