September 26, 2025Journal of Clinical MedicineOpen Access

Systematic Review of Extracorporeal Membrane Oxygenation in Adult Sickle Cell Disease

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Discussion

Systematic review highlights ECMO challenges and outcomes in sickle cell disease patients, emphasizing complications.

VV-ECMO shows a 69% survival rate in patients with respiratory failure due to sickle cell disease.
VA-ECMO has a lower survival rate at 29%, often linked to cardiogenic shock or cardiac arrest.
Complications such as hemorrhage, neurological injury, and thrombosis are significant concerns in ECMO cases.
Larger prospective studies are required to improve ECMO practices in this high-risk population.

Taitoon et al. (2025) studied this question.

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