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September 25, 2025Mediators of InflammationOpen Access

Evaluating the Association Between Neutrophil Gelatinase‐Associated Lipocalin Levels and Periodontal Health Status in Patients With Chronic Kidney Disease

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Authors

AMAhmed MutarMMMaha Sh. Mahmood

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Overview

Cross-sectional analysis found elevated NGAL levels linked to periodontal health in chronic kidney disease patients, indicating potential inflammatory connections.

Key Points

  • NGAL levels were significantly elevated in saliva compared to serum among chronic kidney disease patients, highlighting a notable biomarker.
  • Among 150 patients, 42% in the non-hemodialysis group had periodontitis, indicating a high prevalence of periodontal disease related to CKD.
  • The study employed a cross-sectional design assessing periodontal health and NGAL levels through enzyme-linked immunosorbent tests for serum and saliva.
  • These findings suggest that elevated NGAL levels may serve as important indicators of periodontal health status in CKD patients, with implications for systemic inflammation.

Cite This Study

Mutar et al. (2025) studied this question.

synapsesocial.com/papers/68d5db0cddad3c16d463767chttps://doi.org/10.1155/mi/4114758
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