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September 25, 2025Journal of Pharmacy And Bioallied SciencesOpen Access

Periodontal Disease as a Risk Factor for Depression: A Narrative Review

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Authors

JJanviNCNishant Kumar ChauhanSSSupriya SupriyaRayat Bahra University

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Implication

Narrative review highlights the bidirectional relationship between periodontitis and depression, suggesting further exploration for treatment targets.

Key Points

  • Periodontitis is linked to increased depression risk due to immune dysregulation and inflammation in the central nervous system.
  • Emerging studies indicate that periodontal inflammation plays a crucial role in the pathophysiology of depression.
  • This narrative review discusses several pathophysiological mechanisms connecting periodontitis and depression, urging more research.
  • Elucidating the link between oral health and mood disorders could foster innovative prevention and treatment strategies.

Cite This Study

Janvi et al. (2025) studied this question.

synapsesocial.com/papers/68d5da9cddad3c16d4636dffhttps://doi.org/10.4103/jpbs.jpbs_1052_25
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