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September 25, 2025Journal of Cardiovascular ImagingOpen Access

Current and emerging medical and surgical therapy in hypertrophic cardiomyopathy

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Authors

KKKyung An KimMJMi-Hyang Jung

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Overview

Review highlights current and emerging therapies for hypertrophic cardiomyopathy (HCM), suggesting new approaches for treatment.

Key Points

  • Modern strategies for managing hypertrophic cardiomyopathy (HCM) focus on the underlying disease mechanisms.
  • Sodium-glucose cotransporter 2 inhibitors improve myocardial function while cardiac myosin inhibitors reduce sarcomeric hypercontractility.
  • Established treatments include β-blockers and surgical myectomy, primarily addressing symptoms rather than root causes.
  • Research into gene-targeted therapies is ongoing, potentially offering new avenues for definitive treatment options.

Cite This Study

Kim et al. (2025) studied this question.

synapsesocial.com/papers/68d5da9cddad3c16d4636d3dhttps://doi.org/10.1186/s44348-025-00050-9
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