September 25, 2025LifeOpen Access

The Brazilian Caatinga Biome as a Hotspot for the Isolation of Antibiotic-Producing Actinomycetota

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Isolation of 340 Actinomycetota strains from the Caatinga biome reveals antimicrobial activity, suggesting new antibiotics.

122 isolates from a total of 340 showed antimicrobial activity against pathogens like Escherichia coli.
MALDI-TOF MS analysis identified approximately 32% of strains as belonging to the Streptomyces genus.
The study highlights the Caatinga biome as a rich reservoir for novel bioactive Actinomycetota species.
Metabolomic profiling suggests existing and potentially new antibiotics could aid in combating resistance.

Fernandes et al. (2025) studied this question.

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