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September 25, 2025World Journal of Clinical OncologyOpen Access

Overview of Yttrium-90 radioembolization for advanced hepatocellular carcinoma: Current status and future perspectives

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Authors

HYHaiyang YuCXCheng XieHCHong-Qiao Cai

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Overview

Editorial reveals effectiveness of yttrium-90 radioembolization in managing advanced HCC, highlighting integration with systemic therapies.

Key Points

  • Radioembolization shows improved disease control rates compared to standard systemic therapies like sorafenib.
  • Key trials like SARAH and SIRveNIB demonstrate its efficacy, especially with personalized dosimetry techniques.
  • This technique helps in tumor downstaging and bridging to transplants for patients with advanced liver conditions.
  • Emerging innovations are expected to address current challenges and enhance the application of radioembolization.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd72dc445aa9033b0cbbhttps://doi.org/10.5306/wjco.v16.i9.109730
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Yttrium-90 microsphere therapy for hepatocellular carcinoma: Clinical efficacy, mechanistic insights, and comparative therapeutic perspectives2025
  2. 2Harnessing yttrium-90 selective internal radiation therapy for primary hepatocellular carcinoma: Mechanisms of action and combination strategies2025
  3. 3Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection2025 · 1 citations
  4. 4Radioembolization: Technical Tips and Follow-Up Imaging2025
  5. 5Application and Research Progress of Radiotherapy in Unresectable Hepatocellular Carcinoma2025