A Comparative Evaluation of Dexmedetomidine Infusion versus Normal Saline on Intraoperative Hemodynamic Stability in Laparoscopic Cholecystectomy

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Discussion

Randomized trial assessed hemodynamic stability in patients undergoing laparoscopic cholecystectomy, indicating dexmedetomidine may enhance outcomes.

Dexmedetomidine infusion showed consistently lower hemodynamic parameters during surgery.
Heart rate increased from baseline to post-intubation, with no significant difference between groups.
MAP values were lower in dexmedetomidine group, suggesting better hemodynamic control.
Though not statistically significant, trends favor dexmedetomidine for smoother anesthesia management.

Kotak et al. (2025) studied this question.

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Randomized trial assessed hemodynamic stability in patients undergoing laparoscopic cholecystectomy, indicating dexmedetomidine may enhance outcomes.