September 25, 2025Journal of Clinical MedicineOpen Access

The Burden of Sepsis and Septic Shock in the Intensive Care Unit

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This narrative review outlines sepsis and septic shock burden in ICUs, highlighting diagnostics and management strategies.

Over 48 million cases of sepsis occur annually, with ICU mortality rates ranging from 30 to 50%.
Timely antimicrobial administration and hemodynamic stabilization are critical management strategies in sepsis treatment.
Survivors of sepsis may face long-term impairments known as post-intensive care syndrome (PICS), affecting quality of life.
Integrating precision medicine and addressing disparities are essential for improving sepsis care and outcomes globally.

Via et al. (2025) studied this question.

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