Is Type 2 Diabetes Mellitus an Inflammatory Condition? Exploring the Links Between Interleukin-6, a Pro-Inflammatory Cytokine, Glycemic Indices and Adiposity in Type 2 Diabetes Mellitus
Cross-sectional analysis reveals elevated interleukin-6 levels correlated with glycemic indices in T2DM, indicating inflammation's role in obesity-related diabetes.
Key Points
Interleukin-6 levels are significantly elevated in patients with type 2 diabetes mellitus compared to healthy controls.
Diabetic patients showed a sixfold increase in IL-6 levels, with even higher levels in those with obesity.
A moderate positive correlation exists between IL-6 and BMI, while a strong correlation is observed with HbA1c.
Findings suggest inflammation plays a crucial role in the development of type 2 diabetes, particularly in obese individuals.