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September 25, 2025Microbiology SpectrumOpen Access

Comparison of respiratory pathogen infections in hospitalized patients before and during the COVID-19 pandemic in Shanghai, China

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Authors

XLXiaoxiao LiJWJie WangJDJunhua Dai

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Overview

This observational study reveals a significant decline in respiratory pathogens during the COVID-19 pandemic, indicating changes in infection patterns among hospitalized patients.

Key Points

  • The COVID-19 pandemic led to a notable decrease in respiratory pathogen infections, dropping from 32.05% to 11.48%.
  • Among the common pathogens, Mycoplasma pneumoniae and Legionella pneumophila showed different detection rates before and during the pandemic.
  • Children experienced significantly higher infection rates (73.21%) than adults and older adults, indicating varying vulnerability.
  • Positivity for several respiratory pathogens declined, while detection of Legionella increased, suggesting shifts in respiratory infection dynamics.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd64dc445aa9033b01eahttps://doi.org/10.1128/spectrum.00435-25
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