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September 25, 2025Journal of Translational MedicineOpen Access

Bio fluid exosomes: promises, challenges, and future directions in translational medicine

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Authors

FSFatemeh SoltanmohammadiMMMaryam MaghsoodiEAEffat Alizadeh

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Overview

This review examines exosomes' role as biomarkers and therapeutics in various diseases, highlighting clinical trials and challenges.

Key Points

  • Exosomes serve as promising non-invasive biomarkers for cancers and neurodegenerative diseases, enhancing diagnostic capabilities.
  • Innovative isolation techniques for biofluid-derived exosomes improve their therapeutic applications in drug delivery and regenerative medicine.
  • Clinical trials are underway investigating exosome-based precision medicine, indicating a shift toward more personalized therapeutic strategies.
  • Technical challenges in exosome characterization and isolation remain significant barriers to their widespread clinical application.

Cite This Study

Soltanmohammadi et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd64dc445aa9033b011fhttps://doi.org/10.1186/s12967-025-06886-5
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