September 25, 2025Open Access

From Lab to Life: The Rise of CRISPR-Based Diagnostics for Point-of-Care and Global Health

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This review highlights the evolution of CRISPR diagnostics, emphasizing their role in global health and health equity.

CRISPR-based diagnostics enable sensitive detection of pathogens, enhancing health equity in global health initiatives.
Key applications of these diagnostics include rapid assays for SARS-CoV-2, HIV, and tuberculosis, indicating their effectiveness.
The review covers the unique mechanisms of Cas proteins like Cas12 and Cas13 in signal amplification for accurate diagnostics.
Overcoming challenges in sample preparation and multiplexing is essential for optimizing CRISPR-based diagnostic technologies.

Kiana Sabbaghi (2025) studied this question.

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