Salacca zalacca Skin as a Potential Adjuvant for Metabolic Syndrome Therapy: Integrative In Vitro and Computational Approaches

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Integrative in vitro and in silico approaches evaluated salacca zalacca for metabolic syndrome therapy, suggesting multi-targeted effects.

Salacca zalacca skin showed moderate antioxidant activity and effectively inhibited lipase and α-glucosidase.
Molecular docking revealed strong binding affinities of diphyllin to TNF-α and PPARG, indicating therapeutic potential for metabolic syndrome.
Sixteen bioactive compounds were identified from salacca zalacca skin using LC-MS/MS, highlighting its rich phytochemical profile.
This study is the first to integrate in vitro and in silico methods for investigating salacca zalacca's role in metabolic syndrome management.

Putri et al. (2024) studied this question.

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View Full Paper

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Authors

Integrative in vitro and in silico approaches evaluated salacca zalacca for metabolic syndrome therapy, suggesting multi-targeted effects.

Salacca zalacca skin showed moderate antioxidant activity and effectively inhibited lipase and α-glucosidase.
Molecular docking revealed strong binding affinities of diphyllin to TNF-α and PPARG, indicating therapeutic potential for metabolic syndrome.
Sixteen bioactive compounds were identified from salacca zalacca skin using LC-MS/MS, highlighting its rich phytochemical profile.
This study is the first to integrate in vitro and in silico methods for investigating salacca zalacca's role in metabolic syndrome management.

Putri et al. (2024) studied this question.

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