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September 23, 2025CureusOpen Access

A Comprehensive Review of the Role of Biologics and Small-Molecule Therapies in the Long-Term Management of Crohn’s Disease

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Authors

SZSyeda ZaidiKPKeval B PatelMCMaria Gabriela Cerdas

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Overview

Literature review highlights effectiveness of biologics and small-molecule therapies in Crohn's disease, suggesting new therapeutic approaches.

Key Points

  • Biologics and small-molecule therapies form the main treatment strategy for managing Crohn's disease.
  • The review evaluated multiple studies, including randomized controlled trials and cohort studies, presenting a comprehensive analysis.
  • Treatment positions of biologics like anti-TNF and emerging therapies are discussed for long-term management.
  • Insights into personalized treatment approaches and sequence of therapies emphasize the complexity in clinical decision-making.

Cite This Study

Zaidi et al. (2025) studied this question.

synapsesocial.com/papers/68d4419f713b0b5dfea80454https://doi.org/10.7759/cureus.92901
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