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September 23, 2025International Journal of Current Pharmaceutical ResearchOpen Access

Therapeutic Evaluation of Michelia Champaca on Noise-Induced Hepatorenal Alterations in Rats

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Authors

SMS. MalathiDKDhirendra KumarVVidyashree

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Overview

Observational analysis shows major reductions in liver and kidney damage in Wistar rats, indicating Michelia champaca's protective capabilities.

Key Points

  • Chronic noise exposure significantly increased liver and kidney biomarkers, indicating dysfunction and damage.
  • Administration of Michelia champaca extract markedly reduced these hepatic and renal alterations in both acute and chronic settings.
  • Histopathological evaluations confirmed tissue damage due to noise-induced stress, alongside increased DNA fragmentation.
  • The hepatoprotective and nephroprotective effects of Michelia champaca may stem from its beneficial phytochemical constituents.

Cite This Study

Malathi et al. (2025) studied this question.

synapsesocial.com/papers/68d440a6713b0b5dfea7fda9https://doi.org/10.22159/ijcpr.2025v17i5.7069
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