September 23, 2025MedicinaOpen Access

Rethinking Lymphadenectomy in Cutaneous Melanoma: From Routine Practice to Selective Indication: A Narrative Review

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Discussion

Narrative review highlights a shift from routine lymphadenectomy to selective indications, suggesting improved patient outcomes.

The shift towards selective lymphadenectomy is supported by evidence from pivotal trials underscoring surgical morbidity.
Recent guidelines advocate for sentinel lymph node biopsy as the standard for nodal staging, emphasizing a tailored approach.
Traditional complete lymph node dissection is being limited to select high-risk melanoma patients, reflecting changing practices.
Integration of immunotherapy and ongoing clinical trials are expected to refine surgical strategies significantly.

Matteucci et al. (2025) studied this question.

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