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September 23, 2025Journal of Tropical MedicineOpen Access

Epidemiology of Hepatitis B Virus Infection in Nigeria: A Narrative Review of Prevalence, Transmission, Genotypes, Coinfections, and Mortality

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Authors

BOBabayemi O. OlakundeDADaniel A. AdeyinkaOOOlubunmi A. Olakunde

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Overview

Narrative review reveals high hepatitis B virus prevalence in Nigeria, highlighting transmission dynamics and coinfection patterns.

Key Points

  • High hepatitis B virus prevalence has been observed, with rates between 5.4% and 13.6% in the general population.
  • Approximately 14.4 million people are living with hepatitis B virus in Nigeria, with significant disparities among subpopulations.
  • Genotype E is the predominant strain of hepatitis B virus reported, alongside high rates of coinfections with hepatitis C and HIV.
  • In 2022, around 46,000 deaths were attributed to hepatitis B virus, indicating a mortality rate of 21 per 100,000 population.

Cite This Study

Olakunde et al. (2025) studied this question.

synapsesocial.com/papers/68d43edd713b0b5dfea7ea00https://doi.org/10.1155/jotm/4939367
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyperendemicity and genotype diversity of hepatitis B virus among patients attending the University of Abuja Teaching Hospital, Nigeria.2025 · 1 citations
  2. 2Retrospective Prevalence of Hepatitis B Virus (HBV) and its Associated Risk Factors in Maiduguri, Northeastern Nigeria: A Hospital-Based Study2025
  3. 3Seroprevalence and Correlates of Hepatitis-B Virus Infection among Pregnant Women Attending Antenatal-Clinic at Primary Healthcare Facilities in Nasarawa State, Central Nigeria2025 · 2 citations
  4. 4Prevalence of Hepatitis B Infection and Associated Factors among Students of Tertiary Institution in Ekiti State, Nigeria2025
  5. 5Evolutionary Insights of Hepatitis B Virus Genotypes and Profiles of Mutations in Surface and Basal Core Promoter/Pre-Core Genes Among HBsAg-Positive Patients in North-Central and Southwestern Nigeria2025