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September 23, 2025Emergency Care and MedicineOpen Access

Coronary CT Angiography for Acute Chest Pain in the Emergency Department: A Systematic Review of Clinical Utility

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Authors

KIKyvan IrannejadLHLogan HubbardANAditya Narashim

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Overview

A systematic review shows that coronary CT angiography improves diagnostic accuracy for acute chest pain, highlighting its value for patient outcomes.

Key Points

  • CCTA significantly reduced diagnostic time by up to 54%, enhancing emergency efficiency in the diagnosis of acute chest pain.
  • The review included 23 studies with over 60,000 patients, consistently showing CCTA's pooled sensitivity exceeding 90%, ensuring reliable CAD exclusion.
  • Systematic review methods adhered to PRISMA guidelines, incorporating randomized controlled trials and cohort studies comparing CCTA against standard diagnostic strategies.
  • Findings support CCTA's safety and efficiency in ACS evaluation, but future research is needed to assess its long-term cost-effectiveness.

Cite This Study

Irannejad et al. (2025) studied this question.

synapsesocial.com/papers/68d43ed7713b0b5dfea7e564https://doi.org/10.3390/ecm2030046
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Outcomes of Computed Tomography Coronary Angiography (CTCA) in Patients With Suspected Coronary Artery Disease: A Single‐Center Experience2025
  2. 2Utility of Coronary CT Angiography Versus Functional Stress Testing in Patients With Stable Chest Pain: A Systematic Review2025
  3. 3Diagnostic Accuracy of CT Angiography in Stable Patients Suspected of Obstructive Coronary Artery Disease2025
  4. 4Coronary computed tomography angiography <i>vs</i> stress testing for stable angina evaluation: Diagnostic and prognostic superiority2025
  5. 5Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain2026