Using patient-reported outcomes from the PROCLAIM trial to assess the impact of universal germline genetic testing for prostate cancer patients

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Germline genetic testing for prostate cancer did not lead to significant psychological harm among tested patients.
Among patients with positive results, 93% completed or planned further clinical recommendations based on their test results.
Patients with variant of uncertain significance results showed inconsistencies in understanding and following clinicians' recommendations.
Educational efforts are needed for effectively communicating germline genetic testing results to enhance patient management.

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Secondary analysis assesses psychological impact and clinical recommendations uptake in prostate cancer patients.

Shore et al. (2025) studied this question.

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