Adhesive Gelatin/Chitosan Hydrogel Coating Containing MgO Nanoparticles for Promoting Soft Tissue Integration

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This study demonstrates improved interfacial adhesion and antibacterial properties in soft tissue, suggesting enhanced regeneration.

The hydrogel coating significantly enhances soft tissue integration and shows broad-spectrum antibacterial activity.
In vitro and in vivo studies revealed accelerated collagen deposition and angiogenesis due to MgO nanoparticles.
XPS and 1H NMR analyses confirmed that NHS groups facilitate covalent bonding with plasma-activated PPEK implants.
The design combines physicochemical bonding and ion-mediated bioactivity to optimize implant performance.

Ma et al. (2025) studied this question.

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