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September 23, 2025Anaesthesia Pain & Intensive CareOpen Access

Expression analysis of CCL2, CCL5, and CXCL10 in breast cancer: an insight into the inflammatory microenvironment

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Authors

HZHasanain Akram ZainalbdenEAEbubekir ArslanIAIhsan Edan Alsaimary

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Overview

Observational study found increased levels of CCL2, CCL5, and CXCL10 in breast cancer patients, suggesting their potential as biomarkers.

Key Points

  • Elevated expression of CCL2, CCL5, and CXCL10 was noted in late-stage breast cancer patients, indicating their importance.
  • Clear amplification of chemokine genes was observed through PCR, confirming their presence as potential biomarkers.
  • Analysis involved 100 breast cancer patients and 100 controls, showcasing a comparison critical for understanding disease mechanisms.
  • Findings imply the need for further studies to explore chemokine profiling in treatment planning and prognosis.

Cite This Study

Zainalbden et al. (2025) studied this question.

synapsesocial.com/papers/68d43ed1713b0b5dfea7dfeahttps://doi.org/10.35975/apic.v29i6.2901
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