Novel obesity and metabolic indices better predict non-alcoholic fatty liver disease in elderly T2DM patients: evidence from cross-sectional and longitudinal analysis
Cross-sectional and longitudinal analysis reveals obesity and metabolism indices predict NAFLD in T2DM patients, highlighting potential clinical applications.
Key Points
All obesity and metabolism-related indices significantly predicted non-alcoholic fatty liver disease (NAFLD) risk in elderly T2DM patients.
Odds ratio for LAP was 1.014, while for WHtR it reached 3.288, indicating strong associations with NAFLD risk.
Longitudinal analysis showed that baseline LAP and MetS scores were independently linked to increased risk of developing NAFLD over 25 months.
Time-dependent ROC analysis indicated LAP offered the highest predictive accuracy for NAFLD at 24 months with an AUC of 0.725.