Laboratory tests reveal aloe vera gel extracts show effectiveness against hospital-acquired MRSA infections, indicating potential as an alternative treatment.
Introduction: Aloe vera has a long history as a medicinal plant with numerous therapeutic uses. Methicillin‐resistant Staphylococcus aureus (MRSA) is a type of bacteria resistant to commonly used antibiotics such as penicillin. Hospital‐acquired methicillin‐resistant Staphylococcus aureus (Ha‐MRSA) refers to MRSA infections that arise in healthcare settings, usually 48 h or longer after hospital admission or in individuals with recent hospitalization. This research is aimed at investigating the effectiveness of Aloe vera gel extract against Ha‐MRSA. Methods: The agar well boring diffusion and the broth dilution test methods were employed, respectively, to assess the susceptibility of Ha‐MRSA to Aloe vera gel extract in ethanol and DMSO medium. These extraction media were compared for their effectiveness as the solvent of extraction for the susceptibility test. Results: A minimum inhibitory concentration of 0.2 mg/L of Aloe vera gel extract in the ethanolic extraction medium was achieved, indicating susceptibility of the Ha‐MRSA strain as recommended by EUCAST/ESCMID. Conclusion: Aloe vera gel ethanol extract was sensitive against Ha‐MRSA strains but was resistant in the DMSO extraction method. It is recommended that further research be carried out to ascertain the bioactive compounds responsible for antimicrobial activity.
No takes yet. Share an insight, caveat, or question.
Gyamerah et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: