September 23, 2025CancersOpen Access

Clinical and Molecular Characteristics of 100 Atypical Teratoid Rhabdoid Tumor Patients from Low- and Middle-Income Countries

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Overall survival and event-free survival rates were low at 13% and 12%, reflecting the aggressiveness of ATRT.
Significant factors impacting survival include age under 1 year and the presence of metastatic disease, with 39% of patients diagnosed metastatically.
Meticulous DNA methylation analysis classified patients into molecular subgroups, but no significant survival differences were noted among these groups.
High treatment-related mortality, particularly from septicemia, indicates the need for modified chemotherapy regimens suitable for low socioeconomic status patients.

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Implication

Retrospective cohort study analyzed clinical outcomes in 100 ATRT patients, suggesting improved treatment strategies for low- and middle-income populations.

Cite This Study

Ismail et al. (2025) studied this question.

synapsesocial.com/papers/68d43d75713b0b5dfea7d5f4 https://doi.org/10.3390/cancers17183077

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Implication

Retrospective cohort study analyzed clinical outcomes in 100 ATRT patients, suggesting improved treatment strategies for low- and middle-income populations.

Clinical and Molecular Characteristics of 100 Atypical Teratoid Rhabdoid Tumor Patients from Low- and Middle-Income Countries

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Discussion

Implication

Cite This Study

Clinical and Molecular Characteristics of 100 Atypical Teratoid Rhabdoid Tumor Patients from Low- and Middle-Income Countries

Key Points

Discussion

Implication

Cite This Study

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