Observational analysis identifies blood pressure trajectories affecting clinical outcomes in ischemic stroke patients, suggesting collateral circulation status plays a key role.
Key Points
Patients with high and moderate systolic BP trajectories experienced worse clinical outcomes after endovascular therapy, particularly if they had poor collateral circulation.
Unfavorable outcomes occurred in 7% with a high, 57.9% with moderate, and 35.1% with low systolic BP trajectories, indicating substantial impact based on BP management.
Latent mixture modeling was used to analyze systolic BP trajectories across 800 patients with ischemic stroke due to large-vessel occlusion, focusing on discriminatory outcomes.
The findings highlight the necessity of considering collateral circulation status when managing blood pressure in acute stroke treatment to optimize patient outcomes.