P20 - Phase-dependent effects of vitamin D on oxidative and immune pathways in a rat model of diabetes mellitus

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This study demonstrates vitamin D's antioxidant and anti-inflammatory effects in diabetes mellitus, highlighting its timing-dependent roles.

Vitamin D improves antioxidant activity and reduces inflammation in a rat model of diabetes mellitus.
In the preventive group, vitamin D enhanced catalase activity by day 14 and moderated cytokine levels.
The therapeutic administration of vitamin D increased superoxide dismutase levels, supporting recovery post-diabetes induction.
These findings suggest timing plays a crucial role in vitamin D's effectiveness against oxidative stress and immune decline.

Sakhanberidze et al. (2025) studied this question.

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View Full Paper

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Authors

This study demonstrates vitamin D's antioxidant and anti-inflammatory effects in diabetes mellitus, highlighting its timing-dependent roles.

Vitamin D improves antioxidant activity and reduces inflammation in a rat model of diabetes mellitus.
In the preventive group, vitamin D enhanced catalase activity by day 14 and moderated cytokine levels.
The therapeutic administration of vitamin D increased superoxide dismutase levels, supporting recovery post-diabetes induction.
These findings suggest timing plays a crucial role in vitamin D's effectiveness against oxidative stress and immune decline.

Sakhanberidze et al. (2025) studied this question.

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