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September 22, 2025Acta Anaesthesiologica ScandinavicaOpen Access

Antibiotic Consumption in Danish Intensive Care Units, 2013–2023: A Nationwide Study of Temporal Trends

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Authors

NMNick MeierFHFrederik Boëtius HertzAGAnders Granholm

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Overview

Observational study shows a 21% decrease in antibiotic consumption in ICUs, suggesting effective use policies.

Key Points

  • Antibiotic consumption decreased from 1705 to 1348 defined daily doses per 1000 patient days in Danish ICUs.
  • A substantial reduction of 21% in overall antibiotic usage, driven particularly by a drop in fluoroquinolones and cephalosporins.
  • All adult ICUs in Denmark were included, amounting to a total of 1,121,639 ICU patient days and 1,624,281 DDD administered.
  • This significant decline, without adverse clinical outcomes, highlights effective national antibiotic stewardship efforts.

Cite This Study

Meier et al. (2025) studied this question.

synapsesocial.com/papers/68d43c95713b0b5dfea7cbcdhttps://doi.org/10.1111/aas.70124
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of antibiotic consumption and resistance in intensive care units in France before and during the COVID-19 pandemic2025
  2. 2Trends in hospital antibacterial consumption: a retrospective analysis of reimbursement data, Belgium 2017 to 20222025
  3. 3Evaluation of Hospital Antibiotic Consumption during the COVID-19 Pandemic.2025 · 2 citations
  4. 4The Pattern of Antibiotic Utilization in Intensive Care Units of a Tertiary Care Public Hospital2025
  5. 5Clinical indications for antibiotic prescribing in Danish general practice2025 · 1 citations