Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 21, 2025JGH OpenOpen Access

Diagnostic Performance of Fibrosis‐4 Index, Nonalcoholic Fatty Liver Disease Fibrosis Score, AST‐To‐Platelet Ratio Index, and BARD Score Among Young and Older Adults for the Diagnosis of Advanced MASLD Fibrosis: A Retrospective Cohort Study

View Full Paper
Ask AI
Bookmark
Share

Authors

FLFrank LinAOAyah ObeidMSMehak Sharma

Discussion

Loading...

Member takes

Overview

Retrospective cohort analysis evaluates fibrosis scoring tools' performance for diagnosing advanced fibrosis in MASLD patients, indicating variability in diagnostic accuracy.

Key Points

  • The fib-4 index, NFS, APRI, and BARD scores demonstrate higher negative predictive value for advanced fibrosis, particularly in younger adults.
  • Among young adults with MASLD or MASH, a higher negative predictive value was observed for all four non-invasive scoring tools.
  • Retrospective cohort study analyzed patients over 18, using biopsy findings to evaluate four fibrosis scoring tools for accuracy.
  • Variations in sensitivity, specificity, and AUROC highlight the need for further research on non-invasive scoring modalities and imaging.

Cite This Study

Lin et al. (2025) studied this question.

synapsesocial.com/papers/68d43c8e713b0b5dfea7c8d5https://doi.org/10.1002/jgh3.70281
View Full Paper
Ask AI
Bookmark
Share