September 18, 2025Biomolecules and BiomedicineOpen Access

Arbutin as a potential nephroprotective agent: Dose-related effects in renal ischemia-reperfusion injury

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Experimental analysis shows arbutin counteracts oxidative stress and inflammation in renal injury, suggesting nephroprotective potential.

Arbutin reduces oxidative stress markers in renal ischemia-reperfusion injury, showing protective effects.
In the AR1000+IRI group, ischemia-modified albumin and creatinine levels were significantly lower compared to untreated IRI.
This was a controlled trial with male Wistar albino rats, using doses of arbutin to assess its nephroprotective potential.
The findings indicate arbutin may help prevent kidney damage during ischemia-reperfusion injury, especially at higher doses.

Şirinyıldız et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark