September 17, 2025Journal of Pain ResearchOpen Access

Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study

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Retrospective cohort study examines opioid use and pain outcomes in breast cancer mastectomy patients, highlighting similarities between techniques.

No significant difference in median total opioid use was observed between the erector spinae plane block and pectoralis nerve block options.
Both blocks resulted in comparable PACU pain scores and postoperative nausea and vomiting rates, indicating similar effectiveness.
The analysis included 517 mastectomy patients, noting similar hospital lengths of stay and 30-day readmission rates for both techniques.
Overall, the study found that both blocks offer effective pain management for mastectomy patients without significant differences in outcomes.

Yap et al. (2025) studied this question.

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Retrospective cohort study examines opioid use and pain outcomes in breast cancer mastectomy patients, highlighting similarities between techniques.